In detail

ICP-MS ionizes a digested sample in a high-temperature plasma and separates the ions by mass-to-charge ratio. It can measure many elements in one run at parts-per-billion levels, which is why it is the usual method for heavy-metal panels on botanical extracts.

Sample preparation matters: incomplete digestion, contamination, and matrix effects can all change the result. The certificate should report each element separately, with the limit and the method. A single 'heavy metals' total hides which element failed and at what level.

Why it matters to a buyer

  • Botanical extracts concentrate soil-borne metals along with the desired compounds.
  • Retailers and markets apply different limits by element and product category.
  • Element-specific results are needed to investigate a failed lot or a supplier change.

What to ask a supplier

01

Which elements were tested, and what are the reporting limits?

02

Was the laboratory accredited for this method?

03

Can you provide the raw result for each element rather than a total?

References and further reading

External links are provided for orientation. Requirements differ by market, product, and dose; confirm with your regulatory advisor.

Cite this page

Rainwood Botanical. "Inductively coupled plasma mass spectrometry." Botanical extract glossary, October 2026. https://ingredients.rainwoodbio.com/resources/glossary/icp-ms/